Stimulant-free pre workouts are all the rage these days. Whether it be more people working out later in the evening, too many other stims during the day, or just flat out not handling any dose of stimulant (no matter how small), there’s been a monumental shift over the last six months in the number of athletes embracing stim-free pre workouts.
And why not?
Stimulant-free pre workouts deliver the same performance, focus, and vasodilating benefits of hardcore pre workouts, without the jitters, crash, or disrupted sleep that occasionally accompany stim-based pre workouts.
But, there’s a problem with a lot of the stim-free pre workouts on the market — they’re all copycats of each other. More often than not, stimulant-free pre workouts are only about one thing — the pump.
No one can dispute how awesome it is to get a raging pump going during training, but that’s not all stim-free pre workouts should be about. Stim-free pre workouts should also look to improve blood flow, performance, and oxygen utilization during exercise — the truly important things when it comes to training!
That’s why Condemned Labz created DNA Dispatch.
DNA Dispatch delivers the pumps you demand from a pre workout, but it also has a full arsenal of ingredients to improve vasodilation, increase blood flow, boost nitric oxide production, and enhance oxygen delivery too. The end result is a pre workout that helps you last longer during your workouts, banging out more reps for greater gains and ultimately, better results!
“Peeling Back the Panel” with Condemned CEO Mike Jirovec
Founder and CEO of Condemned Labz, Mike Jirovec, personally formulates every single supplement the company makes. As such, who better to ask than the man behind the product about the purpose, goal, and intention of DNA Dispatch.
Here’s what he had to say:
”When I created DNA Dispatch I saw a lot of copycat products on the market that weren’t effective. Products that were overly marketed, yet so underdosed they couldn’t possibly perform as bold as their claims. So I said to myself ‘how could we make a more superior formula that can really produce optimal results?’
Low and behold we came up with DNA Dispatch.
One of the first methods I used while formulating any product is logic. Yes, common sense, the product needs to make sense. Sometimes the overly scientific stuff complicates things and can even make them counterproductive.
We all know vasodilation (opening of blood vessels that allows for more blood) is a crucial factor in delivering pump. Where DNA Dispatch stands alone is with our oxygen support. Not only did we include all the pump ingredients in there. We also loaded a mushroom blend with enhanced oxygen support.
Oxygen is another major factor in the process. Think about it with more oxygen being generated the blood can flow more effectively to where it is needed. A lot of companies won’t put these ingredients in because they are too costly, ultimately slighting the consumers. We pedestal our brand because we are quality and integrity driven.
We also know that you need a healthy, energized heart to function properly to keep all this blood flowing. We used ingredients for that as well. DNA Dispatch is probably one of the most complete endurance and enhancing formulas on the market.”
PeakO2™ is a patented, proprietary matrix of performance-boosting mushrooms, featuring the Cordyceps militaris, a mushroom widely reputed for its anti-inflammatory, antioxidant, and anti-aging benefits.[1,2] In addition to Cordyceps militaris, PeakO2 also includes Reishi, King Trumpet, Shiitake, Lion’s Mane, and Turkey Tail.
PeakO2 has been documented to improve VO2 Max, peak power output, and time to exhaustion. With PeakO2 you’ll be able to train longer, and have an easier time pushing to those higher thresholds due to the improved oxygen kinetics this supplement delivers.
It benefits fast-twitch athletes (weightlifters, sprinters, etc.) as well as slow-twitch endurance athletes, the same of which can’t be said for other well-known endurance supplements, i.e. beta alanine.
Agmatine Sulfate (1g)
Nitric oxide is an important cell-signaling molecule in the body the increases blood flow and promotes vasodilation. Arginine is the amino acid that fuels nitric oxide synthesis, but there ’s a problem — Arginase, they enzyme that destroys arginine in the body.
Left unchecked, arginase breaks down any excess arginine, meaning your nitric oxide production (and therefore pumps and performance) suffer. That’s where Agmatine comes in.
Agmatine inhibits arginase, promoting uninterrupted nitric oxide production for better blood flow and bigger pumps. On top of that, agmatine also serves as a neurotransmitter, where it increases your tolerance to pain, thereby prolonging stamina and endurance.
Citrulline Malate (1g)
To further support nitric oxide production, and bolster the whopping 4g dose of L-Citrulline in Convict Stim pre workout, Condemned Labz has added in another 1g of citrulline malate. The extra citrulline and malic acid (malate) will improve ammonia buffering, energy production, and nitric oxide production, for better stamina and performance during training.
Glycine Propionyl L-Carnitine (500mg)
Glycine Propionyl L-Carnitine (GPLC) is an oft-overlooked nitric oxide supporting ingredient. GPLC is an incredibly bioavailable form of carnitine noted to enhance vasodilation and endurance. It also combats lactic acid accumulation, thereby reducing the “burning” sensation that can set in during those extended sets, drop sets, and “run the rack” sets you’re likely doing in your workouts.[6,7]
Derived from the BCAA Valine, Norvaline is another extender and protector of nitric oxide production. Similar to Agmatine, norvaline inhibits arginase, allowing for maximum nitric oxide delivery to your muscles during training. More arginine circulating throughout your body means greater blood flow, oxygen and nutrient delivery to your working muscles, boosting (and sustaining) performance and pumps.
Grape Seed Extract (200mg)
Grape seeds are loaded with all kinds of intriguing phytochemicals, including catechins and tannins. These phytonutrients support increased blood flow and cardiovascular health by upregulating nitric oxide production, promoting vasodilation (widening of blood vessels) and thereby improving circulation.[12,13]
In case you were curious, the way the compounds inside grape seeds elevate nitric oxide production is by ramping up endothelial Nitric Oxide Synthase (eNOS), the enzyme that fuels nitric oxide in the body.
Coenzyme Q10 (CoQ10) is a well-known, and widely used, heart health supplement. The reason for its widespread use is that CoQ10 supports natural energy production, enhances cardiovascular function, and combats free radicals. On top of that, CoQ10 also improves HDL cholesterol levels, the good kind of cholesterol![17,18]
Vanadyl Sulfate (15mg)
Also featured in the HumaSlin, vanadyl sulfate is the inorganic form of vanadium, an essential mineral frequently utilized for its insulin-mimicking actions. Vanadium enhances delivery of carbohydrates and protein to skeletal muscles, and has been shown to reduce fasting plasma glucose and hepatic glucose output (HGO).
How to Take
Consume one serving (6 capsules) 20-30 minutes prior to training.
Just because DNA Dispatch is a stimulant-free pre workout doesn’t mean it can only be used by athletes looking to limit their stimulant intake. Quite the opposite, in fact.
DNA Dispatch can be used by all athletes, stim heads and the low/no-stim trainees out there. It can be used on its own, stacked with Locked Down for the ultimate stim-free, muscle swelling stack, or even combined with Convict Stim for the ultimate energy, focus, pumps, and performance experience!
- Das SK, Masuda M, Sakurai A, Sakakibara M. Medicinal uses of the mushroom Cordyceps militaris: Current state and prospects. Fitoterapia. 2010;81(8):961-968. doi:https://doi.org/10.1016/j.fitote.2010.07.010.
- Wang L, Xu N, Zhang J, et al. Antihyperlipidemic and hepatoprotective activities of residue polysaccharide from Cordyceps militaris SU-12. Carbohydr Polym. 2015;131:355-362. doi:10.1016/j.carbpol.2015.06.016.
- Hirsch KR, Mock MG, Roelofs EJ, Trexler ET, Smith-Ryan AE. Chronic supplementation of a mushroom blend on oxygen kinetics, peak power, and time to exhaustion. J Int Soc Sports Nutr. 2015;12(Suppl 1):P45. doi:10.1186/1550-2783-12-S1-P45
- Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial. Pain Med. 2010;11(3):356-368. doi:10.1111/j.1526-4637.2010.00808.x.
- Keynan O, et al. Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial. Pain Med. (2010)
- Palmer RM, Ashton DS, Moncada S Vascular endothelial cells synthesize nitric oxide from L-arginine . Nature. (1988)
- Cosby K, et al; Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation . Nat Med. (2003)
- Modin A, et al; Nitrite-derived nitric oxide: a possible mediator of ‘acidic-metabolic’ vasodilation . Acta Physiol Scand. (2001)
- Mihail V. Pokrovskiy, Mihail V. Korokin, Svetlana A. Tsepeleva, et al., “Arginase Inhibitor in the Pharmacological Correction of Endothelial Dysfunction,” International Journal of Hypertension, vol. 2011, Article ID 515047, 4 pages, 2011. doi:10.4061/2011/515047
- Belviranlı M, et al; Effects of Grape Seed Polyphenols on Oxidative Damage in Liver Tissue of Acutely and Chronically Exercised Rats . Phytother Res. (2012)
- Belviranlı M, et al; Effects of grape seed extract supplementation on exercise-induced oxidative stress in rats . Br J Nutr. (2012)
- Feng Z, et al Grape seed extract enhances eNOS expression and NO production through regulating calcium-mediated AKT phosphorylation in H2O2-treated endothelium. Cell Biol Int. (2010)
- Mohr D, Bowry VW, Stocker R. Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta. 1992 Jun 26;1126(3):247-54.
- Rosenfeldt F, et al Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue . J Thorac Cardiovasc Surg. (2005)
- Watts GF, et al Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus . Diabetologia. (2002)
- Mabuchi H, et al Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study . Atherosclerosis. (2007)
- K. Cusi, S. Cukier, R. A. DeFronzo, M. Torres, F. M. Puchulu, J. C. Pereira Redondo; Vanadyl Sulfate Improves Hepatic and Muscle Insulin Sensitivity in Type 2 Diabetes, The Journal of Clinical Endocrinology & Metabolism, Volume 86, Issue 3, 1 March 2001, Pages 1410–1417, https://doi.org/10.1210/jcem.86.3.7337