There comes a point in every athlete’s life when it’s time to end the perennial bulk and start trimming down. Yeah, yeah, we know you like your food, looking swole, and having those epic carb ups before arm day, but when you really want your muscles to pop, it’s time to cut the fat.
Now, the typical day for the dieter usually involves a lot of exercise and a little bit of calories. While this is great for fat loss, it’s terrible for your energy, mood, focus, and concentration. Your workouts also tend to suffer too, due to the lack of energy and motivation to get in the gym and crush it.
Essentially, in an effort to get lean, you’re sabotaging your mental and physical performance. But, cutting doesn’t have to be as brutal as it used to be thanks to Condemned Labz ARSYN.
What is Arsyn?
Arsyn is a high energy, high focus thermogenic fat burning supplement. Using a mix of powerful central nervous stimulants, nootropics, and lipolytic agents, Arsyn will have you burning calories faster than ever, while feeling better than ever! With Arsyn, hunger and cravings are abolished, ensuring that you cut is as quick and successful as possible, eliminating the dreaded “on again, off again” dieting binges that plague us all.
Let’s see what goes into making the powerful weight loss aid!
Tyrosine is a nonessential amino acid that serves as a precursor to L-Dopa, a compound which subsequently is used to produce dopamine, adrenaline (epinephrine), and noradrenaline (norepinephrine), the critical neurotransmitters that affect mood, focus, and concentration. Tyrosine also helps combat stress and alleviate mental fatigue, both of which come into play when dieting.[1,2]
Caffeine Anhydrous (300mg)
All great fat burners contain caffeine, and Arsyn is packing a heaping dose of the powerful CNS stimulant. Though its most well known for its energy-boosting qualities, caffeine also kickstarts the fat burning process by stimulating lipolysis, and it helps reduce appetite. This becomes especially important as the fatty acids freed by caffeine can help prolong endurance, which typically suffers during periods of dieting.
2-aminoisoheptane is an incredibly powerful CNS stimulant that helps combat the mental and physical fatigue that set in during cutting phases. The next-gen stim exerts mild amphetamine-like qualities, but with less stimulation and cardiovascular impact (a very good thing!). Additionally, 2-aminoisoheptane also prevents the reuptake of dopamine and norepinephrine, meaning that these powerful catecholamines stay active longer in your body, which leads to feelings of euphoria and wakefulness.
White Willow Extract (100mg)
Naturally rich in the aspirin precursor salicylic acid, White Willow has a long history of use as a powerful pain relieving agent. Including it in Arsyn helps relieve the general “achiness” that oftens accompanies dieting phases.[5,6]
Additionally, white willow also serves to mimic the fat-burning effects of the popular ECA (ephedrine, caffeine, aspirin) stack, by combining it with alongside caffeine and synephrine, which is chemically similar to ephedrine.
Experiencing brain fog or the quintessential “fuzzy” feeling is extremely common when dieting. To help you stay sharp, Arsyn includes a whopping 60mg of the potent nootropic, Noopept. This powerful cognitive booster stimulates the AMPA and NMDA receptors in the brain which heightens focus and bolsters memory,[7,8] both of which are less than stellar when you’re low on calories.
Matcha Green Tea (50mg)
Green tea has been consumed for centuries for its numerous health benefits, green tea also improves fat burning due to EGCG’s role in promoting lipolytic actions in the body. Green tea may also help prevent some carbohydrate digestion as well, further reducing calorie intake.
Synephrine HCl (50mg)
Extracted from Citrus Aurantium (Bitter Orange), synephrine is a very powerful agonist of beta-3 adrenoceptors, which leads to increased metabolic rate and lipolysis, as well as reduced food intake.[9,10] Essentially, synephrine helps liberate stored fatty acids to be oxidized (“burned”) for fuel by the body, enabling you to perform your best, even though you’re low on carbs and calories.
Higenamine HCl (50mg)
Higenamine (norcoclaurine) is a naturally occurring beta adrenoceptor agonist, similar to synephrine. It’s found in a number of plants, but predominantly the nandina plant. Long used as an anti-asthmatic agent, higenamine activates beta-2 adrenergic receptors which induce bronchodilation (widening of breathing tube).[11,12] This allows for easier breathing during your fat-burning cardio workouts, improving endurance and overall performance. Additionally, higenamine also increases noradrenaline production, leading to greater mobilization of stored fatty acids (i.e. better fat burning!).
Found alongside synephrine in bitter orange is hordenine, another prominent beta-2 adrenergic receptor agonist. This promotes greater fat burning in the body, but more importantly, hordenine also functions as a noradrenaline reuptake modulator. Essentially, hordenine helps important catecholamines, like noradrenaline, hang around longer in the body, leading to sustained fat burning, energy, and focus.
Cayenne Pepper Powder (25mg)
Readily found in classic Cajun cooking, cayenne is a spicy pepper added for its tongue-numbing heat and spice. The reason cayenne peppers are so pungent is due to the alkaloid capsaicin, which give all chiles their notable “bite”. Capsaicin has been shown to increase fat oxidation and energy expenditure, both of which lead to faster fat loss. Cayenne also helps reduce appetite, providing yet another means to staying on point with your diet and burning more calories.
Grapefruit Extract (25mg)
Grapefruits are naturally rich in several of bioactive compounds (including narignin and naringenin) shown to encourage fat loss support weight loss. Additionally, polyphenols in grapefruit have been shown to inhibit phosphodiesterase (PDE) enzymes. These enzymes are natural energy killers, and by inhibiting them, grapefruit extract can promote longer-lasting energy.
Quite possibly the most prominent stimulant-free fat loss supplement on the market today, Paradoxine is a patent patented extract of Grains of Paradise that helps “brown” fat. In your body there are two types of fat, brown fat and white fat. White fat is the excess energy your body stores, while brown fat is the type of fat used to maintain core temperature.
Paradoxine helps “brown” the white fat on your body, thereby increasing thermogenesis and overall energy expenditure, which leads to faster fat loss![18,19]
As you can see, there’s an awful lot of actives going on here in Arsyn,with more still to come. To ensure that your body puts all of these fat-shredding goodies to maximum use, Arsyn includes 5mg of BioPerine. This notable black pepper extract improves ingredient bioavailability and absorption in the body. On top of that, piperine (the active component in BioPerine) has been noted to exert some potent fat burning and lipid-lowering effects in the body.
Yohimbine HCl (3mg)
No matter how long your diet or how intense you train, you’re bound to have some “stubborn” fat that just won’t go away. That’s where yohimbine comes in.
Derived from the yohimbe tree, yohimbine is a powerful stimulant and alpha-2 receptor antagonist that prevents fat storage, allowing those trouble fat stores to be accessed and burned for energy.[21,22] Even better, yohimbine also helps reduce appetite and lower cravings, allowing you to stay true to your diet, no matter how many temptations may come your way.
Huperzine A (300mcg)
We’ve talked about how brain fog, lack of concentration, and a general sense of being “out of it” occurs when you’re restricting calories. It’s not fun, but all part of the dieting process.
That’s why we’ve included a sizeable 300mcg dose of huperzine a. A prominent focus booster and neuroprotectant, huperzine increases levels of the “learning neurotransmitter” acetylcholine, by preventing its breakdown (via acetylcholinesterase inhibition).
Paired alongside tyrosine and noopept, along with caffeine and the other stimulants discussed above, Arsyn ensures that no matter how low your calories go, you’re always “with it”.
How to Take
Consume one serving (2 capsules) upon waking. Due to the extreme potency of Arsyn, you may wish to begin by taking 1 capsule and assessing tolerance.
- Jongkees BJ, Hommel B, Colzato LS. People are different: tyrosine’s modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function. Frontiers in Psychology. 2014;5:1101. doi:10.3389/fpsyg.2014.01101.
- Young SN. L-Tyrosine to alleviate the effects of stress? Journal of Psychiatry & Neuroscience. 2007;32(3):224.
- Kevin J Acheson, Gérard Gremaud, Isabelle Meirim, Franck Montigon, Yves Krebs, Laurent B Fay, Louis-Jean Gay, Philippe Schneiter, Charles Schindler, Luc Tappy; Metabolic effects of caffeine in humans: lipid oxidation or futile cycling?, The American Journal of Clinical Nutrition, Volume 79, Issue 1, 1 January 2004, Pages 40–46, https://doi.org/10.1093/ajcn/79.1.40
- Ryu, S., Choi, S. K., Joung, S. S., Suh, H., Cha, Y. S., Lee, S., & Lim, K. (2001). Caffeine as a lipolytic food component increases endurance performance in rats and athletes. Journal of Nutritional Science and Vitaminology, 47(2), 139–146.
- Shara, M., and Stohs, S. J. (2015) Efficacy and Safety of White Willow Bark (Salix alba) Extracts. Phytother. Res., 29: 1112–1116. doi: 10.1002/ptr.5377.
- Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Nutrition Journal. 2013;12:154. doi:10.1186/1475-2891-12-154.
- Neznamov, G. G., & Teleshova, E. S. (2009). Comparative studies of Noopept and piracetam in the treatment of patients with mild cognitive disorders in organic brain diseases of vascular and traumatic origin. Neuroscience and Behavioral Physiology, 39(3), 311–321. https://doi.org/10.1007/s11055-009-9128-4
- Ostrovskaya, R. U., Vakhitova, Y. V, Kuzmina, U. S., Salimgareeva, M. K., Zainullina, L. F., Gudasheva, T. A., Seredenin, S. B. (2014). Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. Journal of Biomedical Science, 21(1), 74. https://doi.org/10.1186/s12929-014-0074-2
- Sidney J. Stohs, Harry G. Preuss, and Mohd Shara, “A Review of the Receptor-Binding Properties of p-Synephrine as Related to Its Pharmacological Effects,” Oxidative Medicine and Cellular Longevity, vol. 2011, Article ID 482973, 9 pages, 2011. https://doi.org/10.1155/2011/482973.
- Stohs SJ, Preuss HG, Shara M. A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Oxid Med Cell Longev. 2011;2011:1–9. doi: 10.1155/2011/482973.
- Tsukiyama M, et al. Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. Planta Med. (2009)
- Ueki T, et al. Biphasic tracheal relaxation induced by higenamine and nantenine from Nandina domestica Thunberg. J Pharmacol Sci. (2011)
- Barwell, C. J., Basma, A. N., Lafi, M. A., & Leake, L. D. (1989). Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. The Journal of Pharmacy and Pharmacology, 41(6), 421–423.
- Janssens PLHR, Hursel R, Martens EAP, Westerterp-Plantenga MS. Acute Effects of Capsaicin on Energy Expenditure and Fat Oxidation in Negative Energy Balance. Tomé D, ed. PLoS ONE. 2013;8(7):e67786. doi:10.1371/journal.pone.0067786.
- Yoshioka, M., St-Pierre, S., Drapeau, V., Dionne, I., Doucet, E., Suzuki, M., & Tremblay, A. (1999). Effects of red pepper on appetite and energy intake. The British Journal of Nutrition, 82(2), 115–123.
- Alam MA, Subhan N, Rahman MM, Uddin SJ, Reza HM, Sarker SD. Effect of Citrus Flavonoids, Naringin and Naringenin, on Metabolic Syndrome and Their Mechanisms of Action. Advances in Nutrition. 2014;5(4):404-417. doi:10.3945/an.113.005603.
- Jetter, A. , Kinzig‐Schippers, M. , Walchner‐Bonjean, M. , Hering, U. , Bulitta, J. , Schreiner, P. , Sörgel, F. and Fuhr, U. (2002), Effects of grapefruit juice on the pharmacokinetics of sildenafil. Clinical Pharmacology & Therapeutics, 71: 21-29. doi:10.1067/mcp.2002.121236
- Sugita, J., Yoneshiro, T., et al; “Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men”; British Journal of Nutrition; (2013) 110(4), pp. 733–738;
- Sugita J, Yoneshiro T, et al; “Daily ingestion of grains of paradise (Aframomum melegueta) extract increases whole-body energy expenditure and decreases visceral fat in humans”; Journal of Nutritional Science and Vitaminology; 2014, 60(1): 22-27;
- Shah SS, Shah GB, Singh SD, et al. Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats. Indian Journal of Pharmacology. 2011;43(3):296-299. doi:10.4103/0253-7613.81516.
- Galitzky J, et al; Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers . Eur J Clin Invest. (1988)
- Callahan MF, Beales M, Oltmans GA; Yohimbine and rauwolscine reduce food intake of genetically obese (obob) and lean mice . Pharmacol Biochem Behav. (1984)
- Cheng, D. H., Ren, H., & Tang, X. C. (1996). Huperzine A, a novel promising acetylcholinesterase inhibitor. Neuroreport, 8(1), 97–101.